Buffalo

Birthplace of the original buffalo wings. Still has great wings, pizza, etc.

Bacchus Wine Bar

The wine here is top notch, but so is the eclectic and unique menu.

Pearl Street Grill & Brewery

Free Wireless internet, gourmet chef's, belt driven fans, three patios, and a great bar and game room on the third floor. They brew their own beer in house, and their pulled pork is the best in the city. This place is very busy on nights the Buffalo Sabres (http://buffalosabres.com), the city's professional hockey team is playing at nearby HSBC arena.

Chop House

Constantly busy. A favorite among business travelers. Not cheap, but the food and service is top notch.

Hutch's

One of the best known city restaurants. The Jumbalaya is great, as is the Stuffed Poblano Pepper, which has been a "special" for years.

Left Bank

Another top restaurant in downtown. Like Hutch's getting a weekend reservation can prove difficult. Sunday brunch is typically booked two weeks out.

Prime 490

Newer restaurant, but some of the best food in Buffalo. The steaks are incredible and the sides range from Salt and Vinegar Mashed Potatoes to Lobster Mac n Cheese.

Brand new Cajun/Southern restaurant. Great food and excellent service, with live music. Conveniently located directly across from Shea's Theater on Pearl Street.

Ambrosia

Greek Diner with reasonable prices and a slightly more upscale Mediterranean menu at night.

A popular dive where the latest indie tunes can be heard on the soundsystem and people-watchers can enjoy a clientele that trends heavily toward bohemian urbanites and other alternative types not to mention students of the nearby South Campus of the University at Buffalo, Amy's Place is among the hippest eateries on Main Street. By day they serve a range of Lebanese and other Mediterranean fare of respectable quality, including abundant options for vegetarians and vegans. However, Amy's Place is perhaps best known for their substantial, delicious and reasonably priced breakfasts.